Association for Biology Laboratory Education

A Framework for Using Student-Derived DNA Samples in Laboratory Exercises
    

Kimberly Paczolt and Hao Yiu

Advances in Biology Laboratory Education, 2025, Volume 45

https://doi.org/10.37590/able.v45.abs29

Abstract

The use of student-derived data in the laboratory classroom is an appealing way to increase student engagement, but brings with it a number of ethical concerns, principally that such exercises may reveal aspects of students? genetics which affect their personal identity. We will summarize our approach to using student DNA samples in two laboratory exercises, one using mitochondrial DNA sequence data and another using RFLPs to genotype SNPs associated with lactase persistence. These multi-week laboratory exercises are units of a general education laboratory course called BSCI150: Beyond Race: Human Biological Diversity, at the University of Maryland, College Park. Overall, past students were enthusiastic to participate in these exercises, with many choosing ?analysis of their own DNA? as their favorite aspect of the course. During this workshop, we will walk participants through our effort to balance the novelty of allowing each student to analyze their own DNA with necessary ethical considerations such as informed consent, opt out procedures, and data privacy within each exercise. We will also share the unexpected outcomes, including how this unit structure became an impactful way to facilitate student discussion of research ethics, and the troubleshooting necessary for any participants who would like to use these units in their own courses.

Keywords:  bioethics, personal data, DNA sequencing, informed consent

University of Maryland (2024)