Does Race Exist? Alu Transposable Elements and Ancestry DNA

 

Tested Studies in Laboratory Teaching, 2011, Volume 32

Peggy Brickman & Jim Burnette

Abstract

Alu transposable elements are useful as DNA markers for human population studies. For example, one Alu insertion exists in human populations as 4 different polymorphisms. Interesting variations in the presence of the different alleles in sampled populations from Africa, South America, Europe, and Asia can be used to elucidate human ancestry. In this lab, students examine the genetic basis of race and consider how much genetic variability exists between human populations. Students also experience the excitement of extracting and analyzing their own DNA, performing PCR, restriction enzyme digestion, and gel electrophoresis. The lab can be accomplished in 2 2-hour sessions.

Keywords:  ancestry, transposable element, Alu

Dalhousie University (2010)