An Introduction to Bioinformatics

 

Robert J. Kosinski

Tested Studies in Laboratory Teaching, 2016, Volume 37

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Abstract

This exercise is used in introductory biology for majors at Clemson University. Students download DNA and protein sequences from a Web site and apply common bioinformatics tools to identifying and researching them. The students identify a piece of a gene using BLAST, explore their gene’s genomic “neighborhood,” determine the percent of DNA that is transcribed in this neighborhood, identify a protein using BLAST, research this protein using UniProt, search for literature on the role of the protein in disease, and finally, determine if DNA isolates from a mass disease outbreak show evidence of bioterrorism.

Keywords:  protein, bioinformatics, BLAST, gene, bioterrorism, GenBank, UniProt, PubMed

Boston University (2015)

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