This workshop demonstrated activities & resources from a newly launched lab course that uses diseases as an organizing theme to teach cellular, molecular biological & histological concepts. Lectures use 6 diseases to explore how these concepts interact over time. In lab students learn to extrapolate two-dimensional information from histological tissue sections to three-dimensional tissue structure, and how disease changes tissue structure. In the first half-semester students learn basic general histology. Next, they explore complex tissue organization and slides showing known histopathologies; these include the 6 diseases discussed in lecture, plus tissues from 2-4 related but unknown disease states. They must identify and document abnormal changes in the unknowns relative to matched normal control tissues. For a final project, each student presents their observations and interpretation of one of the unknowns to the class. Workshop participants completed parts of 3 exercises from the lab showing how students explore normal histology, a known disease, and unknown diseases. Supplements include example course documents and an expanded course outline.
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